The Botox effects commonly last between three and four months, depending on factors such as the individual’s metabolism, the area treated, and the dose administered. By some time, the treated muscles gradually regain their ability to contract as the effects of the Botox wear off. Still, regular treatments can help maintain the desired results, and some patients may even notice that the effects last longer with repeated use, as the muscles become more and more trained to stay relaxed. When the effects of Botox diminish, wrinkles and lines will gradually return to their previous appearance, and the individual can choose whether they want to undergo another Botox session to restore the smoothness.